Duloxetine

Duloxetine is a medication. It is sold under the brand name Cymbalta, among others.

Uses

Duloxetine is used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, nerve pain, and other types of chronic pain.[1][2][3] It is taken by mouth.[4]

Function

Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI).[2] This means the medication increases the activity of serotonin and norepinephrine in the brain.[1][2] However, the precise mechanism for duloxetine's antidepressant and anti-anxiety effects is not known.

References

  1. ↑ 1.0 1.1 "Duloxetine (oral route) - Side effects & dosage". Mayo Clinic. Retrieved 2025-09-13.
  2. ↑ 2.0 2.1 2.2 "Duloxetine Delayed-Release Capsules: Uses & Side Effects". Cleveland Clinic. Retrieved 2025-09-13.
  3. ↑ "Medications for OCD". International OCD Foundation. Archived from the original on 27 January 2024. Retrieved 25 February 2024.
  4. ↑ "Duloxetine". Monograph. The American Society of Health-System Pharmacists. Archived from the original on 26 November 2018. Retrieved 13 September 2025.
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