John Little

John Little may refer to:

• John Little (congressman) (1837–1900), U.S. Representative from Ohio
• John Sebastian Little (1851–1916), U.S. Representative from Arkansas
• John William Little, Canadian politician
• John Fletcher Little (1843–1914), Irish physician and politician
• John Little (MP) for City of London

• John Little (American football) (1947–1997), American football player
• John Little (basketball) (born 1984), American basketball player
• John Little (cricketer) (1927–2004), New Zealand cricketer
• John Little (footballer) (1930–2017), Canadian-born Scottish footballer

• John Little (academic) (1928–2024), American academic and operations researcher
• John C. Little (1874–1957), British trade unionist
• John H. Little (born 1941), superintendent of Wentworth Military Academy
• John N. Little, president and co-founder of The MathWorks
• John R. Little (born 1955), dark fiction writer
• John Little (painter) (born 1928), Canadian artist
• John Little (writer) (born 1960), Bruce Lee scholar, bodybuilding/conditioning author, head of the film company JJL Enterprises LLC
• John B. Little (radiobiologist) (1929–2020), American radiobiologist
• John B. Little (mathematician) (born 1956), American mathematician and historian of mathematics

• John Little (department store), a retail chain in Singapore