New Madrid is a city in New Madrid County, Missouri. It is in southeastern Missouri and is on the Mississippi River. At the 2020 census, 2,787 people lived there.
The city was established in 1776 to 1778. It was the scene of the huge 1811–1812 New Madrid earthquakes.
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| Cities | | |
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| Village | |
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| Townships |
- Anderson
- Big Prairie
- Como
- Hough
- La Font
- Le Sieur
- Lewis
- New Madrid
- Portage
- St. John
- West
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Unincorporated communities |
- Bayouville
- Big Ridge
- Boekerton
- Broadwater
- Como
- Conran
- Dodds
- Farrenburg
- Hartzell
- Hurricane Ridge
- Kewanee
- La Forge
- Lorwood
- Noxall
- Point Pleasant
- Ristine
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| Ghost towns |
- Baxter
- East Lake
- Frailie
- Linda
- Ogden
- Selkirk
- Wila
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| Footnotes | ‡This populated place also has portions in an adjacent county or counties |
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