Quantum biology

Quantum biology is the study of quantum mechanics, theoretical chemistry, and biology. This study cannot be explained by classical physics. This is why quantum mechanics must be used.[1]

In biology, there are many processes that involve quantum mechanics. For example, converting (or changing) energy into different forms uses quantum mechanics. Chemical reactions, light absorption, forming excited electronic states and transfer of excitation energy all involve quantum mechanics and biology. Also, electrons and protons (hydrogen ions) move in chemical reactions. These processes make photosynthesis, olfaction and cellular respiration happen.[2]

Quantum biology can use math computations (or calculations) that explain the effects of light in biology.[3]

Quantum biology studies important and unexpected things that happen while studying quantum biology. These important and unexpected things are called "non-trivial quantum phenomena".[4] These phenomena use physics to explain complicated biology processes. However, the physics in quantum biology is very hard to study.[5]

There are 4 common biology processes that are affected by quantum mechanics. These are enzyme catalysis, sensory processing, energy transfers, and information encoding.[6]

Enzyme catalysis

Enzymes are biological catalysts. This means they are living molecules (usually a protein) that makes the reaction rate (or speed) of a chemical reaction go faster. Scientists have learned that enzymes might use quantum tunneling in electron transport chains. Electron transport chains move an electron from one place to another. Enzymes could possibly use quantum tunneling to move electrons along the transport chain.[7][8][9] Quantum tunneling lets more energy to move moved through the electron transport chain.

Proteins have four structures. These structures organize how the protein is formed. The fourth structure is called the protein quaternary structure. Scientists think that the quaternary structures in enzymes have adapted to let quantum entanglement and coherence happen in themselves. Quantum entanglement and coherence are needed for quantum tunneling to happen.[10]

In quantum tunneling, electrons and protons are transferred, or moved. The protons are in the form of an hydrogen ion, or H+.[11][12] Quantum tunneling is when a subatomic particle moves through a "potential energy barrier". In classical physics, the particle would be reflected off this barrier because it does not have enough energy. In quantum tunneling, the particle moves past this barrier.[13] Particles are able to do this because of complementarity. Complementarity is when measuring something changes the thing. Since electrons and protons are both waves and particles, they can move through potential energy barriers.[14][15]

In physics, a semiclassical (SC) physics is useful in explaining this process. This is because it involves both quantum objects (e.g. particles) and larger objects (e.g. biochemicals).[9][16]

References

  1. Kristiansen, Anita. "The future of quantum biology | Royal Society". royalsociety.org. Retrieved 2022-07-11.
  2. Quantum Biology. University of Illinois at Urbana-Champaign, Theoretical and Computational Biophysics Group.
  3. Quantum Biology: Powerful Computer Models Reveal Key Biological Mechanism Science Daily Retrieved Oct 14, 2007
  4. Brookes, J. C. (May 2017). "Quantum effects in biology: golden rule in enzymes, olfaction, photosynthesis and magnetodetection". Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. 473 (2201): 20160822. Bibcode:2017RSPSA.47360822B. doi:10.1098/rspa.2016.0822. PMC 5454345. PMID 28588400.
  5. Al-Khalili, Jim (24 August 2015), How quantum biology might explain life's biggest questions, retrieved 2018-12-07
  6. Brookes, Jennifer C. (May 2017). "Quantum effects in biology: golden rule in enzymes, olfaction, photosynthesis and magnetodetection". Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. 473 (2201): 20160822. Bibcode:2017RSPSA.47360822B. doi:10.1098/rspa.2016.0822. ISSN 1364-5021. PMC 5454345. PMID 28588400.
  7. Marcus, R. A. (May 1956). "On the Theory of Oxidation-Reduction Reactions Involving Electron Transfer. I". The Journal of Chemical Physics. 24 (5): 966–978. Bibcode:1956JChPh..24..966M. doi:10.1063/1.1742723. ISSN 0021-9606. S2CID 16579694.
  8. "Editorial". Photosynthesis Research. 22 (1): 1. January 1989. Bibcode:1989PhoRe..22....1.. doi:10.1007/BF00114760. PMID 24424672. S2CID 264017354.
  9. 9.0 9.1 Gray, H. B.; Winkler, J. R. (August 2003). "Electron tunneling through proteins". Quarterly Reviews of Biophysics. 36 (3): 341–372. doi:10.1017/S0033583503003913. PMID 15029828. S2CID 28174890.
  10. Apte, S.P. Quantum biology: Harnessing nano-technology's last frontier with modified excipients and food ingredients, J. Excipients and Food Chemicals, 5(4), 177–183, 2014
  11. Glickman, Michael H.; Wiseman, Jeffrey S.; Klinman, Judith P. (January 1994). "Extremely Large Isotope Effects in the Soybean Lipoxygenase-Linoleic Acid Reaction". Journal of the American Chemical Society. 116 (2): 793–794. doi:10.1021/ja00081a060. ISSN 0002-7863.
  12. Nagel, Z. D.; Klinman, J. P. (August 2006). "Tunneling and dynamics in enzymatic hydride transfer". Chemical Reviews. 106 (8): 3095–3118. doi:10.1002/chin.200643274. PMID 16895320.
  13. Griffiths, David J. (2005). Introduction to quantum mechanics (2nd ed.). Upper Saddle River, New Jersey: Pearson Prentice Hall. ISBN 0-13-111892-7. OCLC 53926857.
  14. Masgrau, Laura; Roujeinikova, Anna; Johannissen, Linus O.; et al. (April 2006). "Atomic description of an enzyme reaction dominated by proton tunneling". Science. 312 (5771): 237–241. Bibcode:2006Sci...312..237M. doi:10.1126/science.1126002. PMID 16614214. S2CID 27201250.
  15. Zewail, Ahmed H. (2008). Physical biology : from atoms to medicine. London, UK: Imperial College Press. ISBN 978-1-84816-201-3. OCLC 294759396.
  16. Nagel, Z. D.; Klinman, J. P. (August 2006). "Tunneling and dynamics in enzymatic hydride transfer". Chemical Reviews. 106 (8): 3095–3118. doi:10.1021/cr050301x. PMID 16895320.

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