Frontotemporal dementia

Frontotemporal dementia (FTD), or frontotemporal degeneration disease[1] or frontotemporal neurocognitive disorder,[2] includes some types of dementia.[3]


FTD is the clinical presentation of frontotemporal lobar degeneration. It is characterized by progressive neuronal loss predominantly involving the frontal or temporal lobes, and typical loss of over 70% of spindle neurons, while other neuron types remain intact.[4]

Second only to Alzheimer's disease (AD) in prevalence, FTD accounts for 20% of young-onset dementia cases.[5]

Common signs and symptoms include significant changes in social and personal behavior, apathy, blunting of emotions, and deficits in both expressive and receptive language.

Types: One type of FTD, is "semantic-variant primary progressive aphasia, ... that (mostly or) primarily (does something to, or) affects the areas in the brain responsible for speech and language", according to media; Furthermore, one [can have] trouble [remembering] faces and names.[6]

References

  1. ↑ Olney NT, Spina S, Miller BL (May 2017). "Frontotemporal dementia". Neurologic Clinics. 35 (2): 339–374. doi:10.1016/j.ncl.2017.01.008. PMC 5472209. PMID 28410663.
  2. ↑ Diagnostic and statistical manual of mental disorders: DSM-5 (5th ed.). Arlington, Virginia: American Psychiatric Association. 2013. pp. 614–618. ISBN 978-0-89042-554-1.
  3. ↑ "ICD-11 – Mortality and Morbidity Statistics". icd.who.int. World Health Organization. Archived from the original on 2018-08-01.
  4. ↑ "Brain Cells for Socializing". Smithsonian. Retrieved 30 October 2015.
  5. ↑ Snowden JS, Neary D, Mann DM; Neary; Mann (February 2002). "Frontotemporal dementia". Br J Psychiatry. 180 (2): 140–3. doi:10.1192/bjp.180.2.140. PMID 11823324. S2CID 231797268.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. ↑ https://stanfordmag.org/contents/my-brothers-keeper. Retrieved 2025-08-15


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